THERAPEUTIC COMPARISON OF SURGERY COMBINED WITH CHEMOTHERAPY AND CHEMOTHERAPY ALONE FOR PRIMARY GASTROINTESTINAL LYMPHOMA: A SINGLE CENTER STUDY

Therapeutic comparison of Surgery combined with chemotherapy and chemotherapy alone for Primary Gastrointestinal Lymphoma: A single center study

Abstract Objectives There is still no consensus on the optimal treatment for primary gastrointestinal lymphoma (PGIL).The aim of this study was to compare surgery combined with chemotherapy and chemotherapy alone in PGIL.Methods We retrospectively reviewed and analyzed the treatment outcomes of 107 patients with primary gastrointestinal lymphoma di

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AAV Vectors Pseudotyped with Capsids from Porcine and Bovine Species Mediate In Vitro and In Vivo Gene Delivery

Adeno-associated virus (AAV) vectors are among the most widely used delivery vehicles for in vivo gene therapy as they mediate robust and sustained transgene expression with limited toxicity.However, a significant impediment to the broad clinical success of AAV-based therapies is the widespread presence of pre-existing humoral immunity to AAVs in t

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Sorting Tubules Regulate Blood-Brain Barrier Transcytosis

Transcytosis across the Multimedia Platform Bedframe blood-brain barrier (BBB) regulates key processes of the brain, but the intracellular sorting mechanisms that determine successful receptor-mediated transcytosis in brain endothelial cells (BECs) remain unidentified.Here, we used Transferrin receptor-based Brain Shuttle constructs to investigate

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Prevalence of depressive and anxiety symptoms in chronically ill children and adolescents during COVID-19 pandemic and lockdown: Preliminary findings of a pediatric hospital in Italy

Introduction Psychological problems are NORMAL TO DRY HAIR SHAMPOO common among the pediatric population suffering from a chronic illness, especially compared to the normal population.Stressful life events, such as social distancing measures implemented to counter the COVID-19 pandemic emergency, can strongly influence their epidemiology.Objectives

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